Description

tert-Butyl 3-Amino-3-(2-Hydroxyethyl)Piperidine-1-Carboxylate is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its bifunctional nature, featuring both a protected amine and a terminal hydroxyl group, which allows for selective and sequential derivatization. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the construction of complex molecules, including active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its piperidine scaffold.
• Chemical Biology & Proteomics: Serves as a versatile linker or spacer molecule in the design of biochemical probes and affinity tags.
• Peptidomimetics & Scaffold Design: The 3-amino-3-(2-hydroxyethyl)piperidine core is a valuable scaffold for creating conformationally constrained peptide analogs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.
• Academic & Industrial R&D: Employed in discovery chemistry for library synthesis and structure-activity relationship (SAR) studies.

Basic Information

Product Name	tert-Butyl 3-Amino-3-(2-Hydroxyethyl)Piperidine-1-Carboxylate
CAS No.	1263773-99-4
Molecular Formula	C12H24N2O3
Molecular Weight	244.33 g/mol
Synonyms	1-Boc-3-amino-3-(2-hydroxyethyl)piperidine; tert-Butyl 3-amino-3-(2-hydroxyethyl)piperidine-1-carboxylate; 3-Amino-3-(2-hydroxyethyl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-3-amino-3-(2-hydroxyethyl)piperidine; 3-(2-Hydroxyethyl)-3-aminopiperidine-1-carboxylic acid tert-butyl ester; 3-Amino-3-(2-hydroxyethyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; Boc-3-A-3-HEP
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 3-Amino-3-(2-Hydroxyethyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.