Description

1-(2-Chloro-Pyridin-4-Yl)-2,2,2-Trifluoro-Ethanol is a high-value fluorinated pyridine derivative, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its unique structure, combining a halogenated pyridine ring with a trifluoroethanol moiety, makes it indispensable for constructing complex molecules with tailored properties. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Building block for developing new-generation herbicides and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Intermediate for synthesizing specialty polymers and liquid crystals, where the pyridine and fluorine groups influence thermal and optical properties.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and fluorinated tags used in biochemical and diagnostic research.

Basic Information

Product Name	1-(2-Chloro-Pyridin-4-Yl)-2,2,2-Trifluoro-Ethanol
CAS No.	1263400-50-5
Molecular Formula	C7H5ClF3NO
Molecular Weight	211.57 g/mol
Synonyms	2,2,2-Trifluoro-1-(2-chloropyridin-4-yl)ethanol; 1-(2-Chloro-4-pyridinyl)-2,2,2-trifluoroethanol; 4-(2,2,2-Trifluoro-1-hydroxyethyl)-2-chloropyridine; α-(Trifluoromethyl)-2-chloro-4-pyridinemethanol; 2-Chloro-4-(2,2,2-trifluoro-1-hydroxyethyl)pyridine; (2-Chloropyridin-4-yl)(trifluoromethyl)methanol
EINECS	Contact for details

Quality Control

Our production of 1-(2-Chloro-Pyridin-4-Yl)-2,2,2-Trifluoro-Ethanol adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity for research and commercial use. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP compliance for pharmaceutical applications and can provide material manufactured under quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.