Description

1-(1-Phenyl-Cyclopropyl)-Piperazine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and research chemical. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and psychiatric drug discovery. It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical synthesis companies seeking reliable, high-quality raw materials for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel psychoactive substances and potential therapeutic agents targeting neurological receptors.
• Medicinal Chemistry Research: Used as a versatile scaffold in drug discovery programs for structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in the construction of complex piperazine-containing heterocycles for various chemical libraries.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.
• Biochemical Research: Utilized in biochemical assays and as a ligand in pharmacological studies to investigate receptor interactions.

Basic Information

Product Name	1-(1-Phenyl-Cyclopropyl)-Piperazine Dihydrochloride
CAS No.	1263378-62-6
Molecular Formula	C13H18N2·2HCl
Molecular Weight	283.21 g/mol (Free base: 202.30 g/mol)
Synonyms	1-(1-Phenylcyclopropyl)piperazine dihydrochloride; 1-(1-Phenyl-cyclopropyl)-piperazine hydrochloride (1:2); 1-Phenylcyclopropylpiperazine dihydrochloride; 1-(1-Phenylcyclopropyl)piperazine HCl; 1-(1-Phenyl-cyclopropyl)piperazine dihydrochloride salt; 1263378-62-6; 1-(1-Phenyl-cyclopropyl)-piperazine, dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(1-Phenyl-Cyclopropyl)-Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.