Description

Hexahydro-1H-Pyrido[1,2-A]Pyrazin-4(6H)-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block with the CAS number 1263378-28-4. This compound is of significant value in medicinal chemistry for its role as a key precursor in the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and other specialized drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug discovery.
• Preclinical Development: Serves as a key starting material for producing compounds for pharmacological and toxicological evaluation.
• Chemical Synthesis: Employed in academic and industrial laboratories for constructing fused heterocyclic systems with potential biological activity.
• Process Chemistry: Used in route scouting and scale-up studies for the efficient production of target molecules.

Basic Information

Product Name	Hexahydro-1H-Pyrido[1,2-A]Pyrazin-4(6H)-One Hydrochloride
CAS No.	1263378-28-4
Molecular Formula	C9H15N2O·HCl
Molecular Weight	202.69 g/mol
Synonyms	1,2,3,4,6,7-Hexahydro-8H-pyrido[1,2-a]pyrazin-8-one hydrochloride; 4-Oxo-1,2,3,4,6,7-hexahydro-8H-pyrido[1,2-a]pyrazine hydrochloride; 8H-Pyrido[1,2-a]pyrazin-8-one, 1,2,3,4,6,7-hexahydro-, hydrochloride; Hexahydropyrido[1,2-a]pyrazin-4(6H)-one hydrochloride; 1263378-28-4
EINECS	Contact for details

Quality Control

Our Hexahydro-1H-Pyrido[1,2-A]Pyrazin-4(6H)-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.