Description

2-Hydroxymethyl-Piperazine-1,4-Dicarboxylic Acid 4-Allyl Ester 1-tert-Butyl Ester is a high-purity, multi-functional chemical building block designed for advanced synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture in complex organic frameworks. It is primarily utilized in the development of novel active pharmaceutical ingredients (APIs), specialty polymers, and advanced agrochemical intermediates where its unique ester-protected piperazine core offers versatile reactivity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for protease inhibitors, kinase inhibitors, and other small molecule therapeutics.
• Peptide Mimetic Synthesis: Used to construct constrained peptide analogs and peptidomimetics due to its piperazine scaffold and orthogonal protecting groups.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties, leveraging the allyl ester for further modification.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Useful for constructing complex chelating ligands in coordination chemistry and catalysis.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and molecular probes for biochemical and cellular studies.

Basic Information

Product Name	2-Hydroxymethyl-Piperazine-1,4-Dicarboxylic Acid 4-Allyl Ester 1-tert-Butyl Ester
CAS No.	1263282-80-9
Molecular Formula	C15H24N2O5
Molecular Weight	312.36 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-4-(allyloxycarbonyl)-2-(hydroxymethyl)piperazine; 2-(Hydroxymethyl)-1,4-piperazinedicarboxylic Acid 1-tert-Butyl Ester 4-Allyl Ester; 1-Boc-4-Allyloxycarbonyl-2-hydroxymethylpiperazine; Piperazine-1,4-dicarboxylic acid, 2-(hydroxymethyl)-, 1-(1,1-dimethylethyl) 4-(2-propen-1-yl) ester; tert-Butyl 4-(allyloxycarbonyl)-2-(hydroxymethyl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 2-Hydroxymethyl-Piperazine-1,4-Dicarboxylic Acid 4-Allyl Ester 1-tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.