Description

2-(4-(tert-Butoxycarbonyl)-1-(Methoxycarbonyl)Piperazin-2-Yl)Acetic Acid is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, multi-functional scaffold for constructing complex molecules with precise stereochemistry. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Peptidomimetic Synthesis: Used to construct constrained peptide analogs and protease inhibitors due to its piperazine core.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Custom Chemical Synthesis: Provides a versatile handle for medicinal chemistry and process development in contract research and manufacturing (CRO/CMO).
• Academic Research: Utilized in university and institutional labs for methodological studies and exploring new chemical space.

Basic Information

Product Name	2-(4-(tert-Butoxycarbonyl)-1-(Methoxycarbonyl)Piperazin-2-Yl)Acetic Acid
CAS No.	1263280-32-5
Molecular Formula	C13H22N2O6
Molecular Weight	302.33 g/mol
Synonyms	Boc-N(COOMe)-CH2COOH-Piperazine; 1-(Methoxycarbonyl)-4-(tert-butoxycarbonyl)piperazine-2-acetic acid; 2-[4-(tert-Butoxycarbonyl)-1-(methoxycarbonyl)-2-piperazinyl]acetic acid; (2R/S)-2-[4-[(2-Methylpropan-2-yl)oxycarbonyl]-1-(methoxycarbonyl)piperazin-2-yl]acetic acid; N-Boc-N'-COOMe-Piperazine-2-acetic Acid; tert-Butyl 2-(carboxymethyl)-4-(methoxycarbonyl)piperazine-1-carboxylate; 1263280-32-5
EINECS	Contact for details

Quality Control

Our 2-(4-(tert-Butoxycarbonyl)-1-(Methoxycarbonyl)Piperazin-2-Yl)Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.