Description

6-Cyclopropyl-3-Isobutylisoxazolo[5,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the fused isoxazolopyridine class of heterocyclic compounds. This compound is a critical building block in modern medicinal chemistry, valued for its unique molecular scaffold that enables the synthesis of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for drug discovery programs.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• CNS Drug Development: Employed in the research and development of potential therapeutics targeting neurological disorders.
• Anti-inflammatory Agent Synthesis: Acts as a building block for creating new candidates with potential anti-inflammatory properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study biological pathways and protein functions.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Product Name	6-Cyclopropyl-3-Isobutylisoxazolo[5,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1263209-11-5
Molecular Formula	C15H16N2O3
Molecular Weight	272.30 g/mol
Synonyms	6-Cyclopropyl-3-(2-methylpropyl)isoxazolo[5,4-b]pyridine-4-carboxylic acid; 4-Isoxazolopyridine-4-carboxylic acid, 6-cyclopropyl-3-(2-methylpropyl)-; Isoxazolo[5,4-b]pyridine-4-carboxylic acid, 6-cyclopropyl-3-isobutyl-; 1263209-11-5; 6-Cyclopropyl-3-isobutyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Cyclopropyl-3-Isobutylisoxazolo[5,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with the stringent requirements of pharmaceutical R&D and cGMP intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled and stored away from strong light sources. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.