Description

tert-Butyl 9,9-Difluoro-2,7-Diazaspiro[4.5]Decane-7-Carboxylate is a high-value, fluorinated spirocyclic building block designed for advanced pharmaceutical and agrochemical research. This compound is critical for medicinal chemists seeking to modulate the physicochemical and metabolic properties of drug candidates through the strategic incorporation of fluorine and a rigid, three-dimensional scaffold. It is primarily utilized by R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS), oncology, and antiviral therapeutic areas.
• Medicinal Chemistry Scaffold: Used to introduce conformational restraint and fluorine atoms into lead compounds to improve potency, metabolic stability, and membrane permeability.
• Agrochemical Research: Serves as a sophisticated intermediate in the development of new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Biology Probe Development: Employed in the construction of molecular probes for studying enzyme function and biological pathways.
• Library Synthesis for High-Throughput Screening: Used to generate focused libraries of spirocyclic compounds for biological screening against novel targets.

Basic Information

Product Name	tert-Butyl 9,9-Difluoro-2,7-Diazaspiro[4.5]Decane-7-Carboxylate
CAS No.	1263180-38-6
Molecular Formula	C13H22F2N2O2
Molecular Weight	276.33 g/mol
Synonyms	7-Boc-9,9-difluoro-2,7-diazaspiro[4.5]decane; tert-Butyl 9,9-difluoro-2,7-diazaspiro[4.5]decane-7-carboxylate; 9,9-Difluoro-2,7-diazaspiro[4.5]decane-7-carboxylic acid tert-butyl ester; 2,7-Diazaspiro[4.5]decane-7-carboxylic acid, 9,9-difluoro-, 1,1-dimethylethyl ester; Boc-9,9-difluoro-2,7-diazaspiro[4.5]decane; 1263180-38-6
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 9,9-Difluoro-2,7-Diazaspiro[4.5]Decane-7-Carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via NMR and MS. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.