Description

(R)-4-Boc-5-Hydroxymethyl-2,2-Dimethyl-Morpholine CAS NO 1263078-13-2 is a high-purity, chiral morpholine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, where precise stereochemistry is paramount. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of complex molecules for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, particularly in medicinal chemistry.
• Asymmetric Synthesis: Used as a versatile building block for constructing complex molecules with defined stereocenters.
• Ligand and Catalyst Development: Employed in the synthesis of chiral ligands and organocatalysts for enantioselective transformations.
• Peptidomimetics Research: Serves as a constrained scaffold in the design and synthesis of peptide analogs and mimetics.
• Agrochemical Synthesis: Potential intermediate in the development of advanced, chiral agrochemicals.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry and new reaction development.

Basic Information

Product Name	(R)-4-Boc-5-Hydroxymethyl-2,2-Dimethyl-Morpholine
CAS No.	1263078-13-2
Molecular Formula	C12H23NO5
Molecular Weight	261.31 g/mol
Synonyms	(R)-tert-Butyl 5-(hydroxymethyl)-2,2-dimethylmorpholine-4-carboxylate; (R)-4-(tert-Butoxycarbonyl)-5-(hydroxymethyl)-2,2-dimethylmorpholine; (R)-N-Boc-5-Hydroxymethyl-2,2-Dimethylmorpholine; (R)-Boc-Protected Hydroxymethyl Dimethylmorpholine; (R)-4-Boc-2,2-Dimethyl-5-morpholinemethanol; (R)-2,2-Dimethyl-5-(hydroxymethyl)morpholine-4-carboxylic acid tert-butyl ester; (R)-5-(Hydroxymethyl)-2,2-dimethylmorpholine-4-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our (R)-4-Boc-5-Hydroxymethyl-2,2-Dimethyl-Morpholine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive analytical data including HPLC, NMR, and optical rotation to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.