Description

1-Benzyl-4-Hydroxypiperidine-4-Carboxylic Acid Hydrochloride is a high-purity pharmaceutical intermediate and versatile synthetic building block. Its value lies in its functionalized piperidine core, which is a privileged scaffold in medicinal chemistry for constructing bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of potential drug candidates targeting the central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those with neurological or receptor-modulating activity.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic compounds.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides due to its heterocyclic structure.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under GMP or ISO guidelines.
• Academic & Institutional R&D: Employed in university and research institute laboratories for exploratory synthetic chemistry and novel methodology development.

Basic Information

Product Name	1-Benzyl-4-Hydroxypiperidine-4-Carboxylic Acid Hydrochloride
CAS No.	1262988-77-1
Molecular Formula	C14H19NO3·HCl
Molecular Weight	285.77 g/mol
Synonyms	4-Hydroxy-1-benzyl-4-piperidinecarboxylic acid hydrochloride; 1-Benzyl-4-hydroxyisonipecotic acid hydrochloride; 4-(Hydroxy)-1-(phenylmethyl)-4-piperidinecarboxylic acid hydrochloride; 4-Hydroxy-1-benzylpiperidine-4-carboxylic acid HCl; BHPC HCl; 1-Benzyl-4-hydroxypiperidine-4-carboxylic acid HCl salt
EINECS	Contact for details

Quality Control

Our 1-Benzyl-4-Hydroxypiperidine-4-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.