Description

(S)-tert-Butyl 2-(2-Methoxy-2-Oxoethyl)Piperazine-1-Carboxylate CAS NO 1262892-01-2 is a high-purity, chiral piperazine derivative and a crucial protected intermediate in advanced organic synthesis. Its primary value lies in enabling the stereoselective construction of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality building blocks for drug discovery and process optimization.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and infectious diseases.
• API Development: Used in the research and process development stages for constructing complex molecular scaffolds with defined stereochemistry.
• Peptidomimetics & Bioactive Molecules: Serves as a constrained dipeptide surrogate or a functionalized piperazine core in the design of protease inhibitors and receptor modulators.
• Agrochemical Synthesis: Employed as a building block for creating chiral active ingredients with specific biological activity.
• Asymmetric Catalysis Ligand Precursor: Can be utilized to develop novel chiral ligands for asymmetric hydrogenation and other catalytic transformations.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high stereochemical purity and reliable scalability.

Basic Information

Product Name	(S)-tert-Butyl 2-(2-Methoxy-2-Oxoethyl)Piperazine-1-Carboxylate
CAS No.	1262892-01-2
Molecular Formula	C12H22N2O4
Molecular Weight	258.32 g/mol
Synonyms	1-Boc-3-(2-methoxy-2-oxoethyl)piperazine, (S)-enantiomer; (S)-1-(tert-Butoxycarbonyl)-2-(2-methoxy-2-oxoethyl)piperazine; (S)-tert-Butyl 2-(carboxymethyl)piperazine-1-carboxylate methyl ester; (S)-Boc-piperazine-2-acetic acid methyl ester; (S)-Methyl 2-(1-Boc-piperazin-2-yl)acetate; (S)-2-(1-Boc-piperazin-2-yl)acetic acid methyl ester; (S)-1-Boc-2-(methoxycarbonylmethyl)piperazine; (S)-tert-Butyl 2-(methoxycarbonylmethyl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 2-(2-Methoxy-2-Oxoethyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard pharmacopeial identification tests, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.