Description

3-Chloro-5-Hydroxy-Pyridine-2-Carbonitrile is a high-value pyridine derivative and versatile chemical building block. This compound is crucial for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, due to its reactive chloro, hydroxy, and nitrile functional groups. It is primarily sought after by research institutions and industrial manufacturers developing active pharmaceutical ingredients (APIs), advanced crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed coupling reactions and organometallic chemistry.
• Material Science Research: Employed in the research and development of organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific pyridine scaffolds.

Basic Information

Product Name	3-Chloro-5-Hydroxy-Pyridine-2-Carbonitrile
CAS No.	1262860-70-7
Molecular Formula	C6H3ClN2O
Molecular Weight	154.55 g/mol
Synonyms	2-Cyano-3-chloro-5-hydroxypyridine; 5-Hydroxy-3-chloropyridine-2-carbonitrile; 3-Chloro-5-hydroxypicolinonitrile; 3-Chloro-5-pyridinol-2-carbonitrile; 2-Pyridinecarbonitrile, 3-chloro-5-hydroxy-; Picolinonitrile, 3-chloro-5-hydroxy-
EINECS	Contact for details

Quality Control

Our 3-Chloro-5-Hydroxy-Pyridine-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.