Description

Methyl 5-(Hydroxymethyl)Pyrazine-2-Carboxylate is a high-purity pyrazine derivative serving as a versatile and critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a reliable, high-quality intermediate to construct complex molecular architectures. It is primarily targeted at the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyrazine core for biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and light-emitting components, due to its conjugated heterocyclic structure.
• Peptidomimetics and Bio-conjugates: The hydroxymethyl and ester functional groups make it suitable for constructing peptide analogs and bioconjugation linkers.
• Academic and R&D Laboratories: A valuable reagent for medicinal chemistry programs and exploratory research in heterocyclic chemistry.

Basic Information

Item	Details
Product Name	Methyl 5-(Hydroxymethyl)Pyrazine-2-Carboxylate
CAS No.	1262803-64-4
Molecular Formula	C7H8N2O3
Molecular Weight	168.15 g/mol
Synonyms	Methyl 5-(hydroxymethyl)pyrazine-2-carboxylate; 5-(Hydroxymethyl)pyrazine-2-carboxylic acid methyl ester; Methyl 5-hydroxymethylpyrazine-2-carboxylate; 2-Pyrazinecarboxylic acid, 5-(hydroxymethyl)-, methyl ester; Methyl (hydroxymethyl)pyrazinecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 5-(Hydroxymethyl)Pyrazine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available for every shipment. We support compliance with cGMP, ICH guidelines, and other relevant regulatory frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.