Description

1H-Pyrazolo[4,3-B]Pyridine, 5-Bromo-3-(Trifluoromethyl)- is a high-value, multi-functional heterocyclic building block essential for advanced chemical synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its unique heterocyclic structure for biological activity.
• Material Science: Serves as a building block for organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient pyrazolopyridine core.
• Chemical Biology: Employed as a molecular probe or tag in medicinal chemistry and biochemical research to study protein-ligand interactions.
• Custom Synthesis: A critical starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	1H-Pyrazolo[4,3-B]Pyridine, 5-Bromo-3-(Trifluoromethyl)-
CAS No.	1262639-31-5
Molecular Formula	C7H3BrF3N2
Molecular Weight	251.01 g/mol
Synonyms	5-Bromo-3-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine; 5-Bromo-3-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine; 5-Bromo-3-trifluoromethyl-1H-pyrazolo[4,3-b]pyridine; 1H-Pyrazolo[4,3-b]pyridine, 5-bromo-3-(trifluoromethyl)-; 1262639-31-5; 5-Br-3-CF3-pyrazolo[4,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[4,3-B]Pyridine, 5-Bromo-3-(Trifluoromethyl)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing all specifications are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.