Description

(R)-3-Cyanomorpholine is a high-value, chiral building block and key intermediate in organic synthesis. Its unique structure, featuring a morpholine ring with a cyano group at the 3-position in the (R)-enantiomeric form, makes it indispensable for constructing complex molecules with specific stereochemistry. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of novel therapeutic agents, particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced, enantiomerically pure pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology & Proteomics: Employed as a building block for activity-based probes and molecular tools to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic Research: Utilized in university and institutional laboratories for methodological development in synthetic organic chemistry and medicinal chemistry.

Basic Information

Product Name	(R)-3-Cyanomorpholine
CAS No.	1262484-54-7
Molecular Formula	C5H8N2O
Molecular Weight	112.13 g/mol
Synonyms	(R)-Morpholine-3-carbonitrile; (3R)-Morpholine-3-carbonitrile; (R)-3-Cyano-morpholine; (R)-Tetrahydro-2H-1,4-oxazine-3-carbonitrile; (R)-3-Morpholinecarbonitrile; 1262484-54-7; (R)-enantiomer of 3-Cyanomorpholine
EINECS	Contact for details

Quality Control

Our (R)-3-Cyanomorpholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (HPLC), enantiomeric excess (Chiral HPLC), and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.