Description

5-(4-Chlorophenyl)-6-Hydroxynicotinic Acid is a high-purity, functionalized nicotinic acid derivative that serves as a critical advanced intermediate in modern organic synthesis. This compound matters for its role as a versatile building block, enabling the construction of complex molecules with specific pharmacological or agrochemical activities. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, or plant growth regulators requiring a chlorophenyl-hydroxypyridine scaffold.
• Chemical Research: Serves as a versatile building block in academic and industrial laboratories for heterocyclic chemistry and structure-activity relationship (SAR) studies.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and performance materials.
• Ligand and Catalyst Development: Potential precursor for creating novel chelating ligands or organocatalysts due to its carboxylic acid and hydroxyl functional groups.

Basic Information

Product Name	5-(4-Chlorophenyl)-6-Hydroxynicotinic Acid
CAS No.	1262010-75-2
Molecular Formula	C12H8ClNO3
Molecular Weight	249.65 g/mol
Synonyms	6-Hydroxy-5-(4-chlorophenyl)nicotinic acid; 5-(p-Chlorophenyl)-6-hydroxynicotinic acid; 6-Hydroxy-5-(4-chlorophenyl)-3-pyridinecarboxylic acid; 3-Pyridinecarboxylic acid, 6-hydroxy-5-(4-chlorophenyl)-; 1262010-75-2; 5-(4-Chlorophenyl)-6-hydroxy-3-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(4-Chlorophenyl)-6-Hydroxynicotinic Acid is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.