Description

6-(4-Fluoro-3-Methoxyphenyl)Picolinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct substituted phenylpicolinic acid structure. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular scaffolds. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its fluorinated aromatic system.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and material science.
• Chemical Biology Probes: Employed in the design of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: Foundation for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis for clients.

Basic Information

Product Name	6-(4-Fluoro-3-Methoxyphenyl)Picolinic Acid
CAS No.	1261977-99-4
Molecular Formula	C₁₃H₁₀FNO₃
Molecular Weight	247.22 g/mol
Synonyms	2-Pyridinecarboxylic acid, 6-[4-fluoro-3-methoxyphenyl]-; 6-(4-Fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid; 6-(4-Fluoro-3-methoxyphenyl)-2-picolinic acid; 1261977-99-4; 4-Fluoro-3-methoxy-[2,2'-bipyridine]-6-carboxylic acid (alternative); FMPA (abbreviation); 6-(4-Fluoro-3-methoxyphenyl)-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 6-(4-Fluoro-3-Methoxyphenyl)Picolinic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity specifications suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.