Description

6-(3-Chloro-5-Fluorophenyl)Picolinic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular scaffolds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries engaged in developing new small-molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its halogenated phenylpyridine core.
• Chemical Synthesis: Serves as a versatile precursor for creating more complex heterocyclic compounds in medicinal chemistry.
• Material Science Research: Potential monomer or additive in the development of specialized polymers and advanced materials.
• Academic & R&D: Utilized in university and corporate laboratories for structure-activity relationship (SAR) studies and novel compound libraries.

Basic Information

Product Name	6-(3-Chloro-5-Fluorophenyl)Picolinic Acid
CAS No.	1261932-98-2
Molecular Formula	C₁₂H₇ClFNO₂
Molecular Weight	251.64 g/mol
Synonyms	6-(3-Chloro-5-fluorophenyl)pyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 6-(3-chloro-5-fluorophenyl)-; 3-Chloro-5-fluoro-[2,2'-bipyridine]-6-carboxylic acid (related); Picolinic acid, 6-(3-chloro-5-fluorophenyl)-; 1261932-98-2; 6-(3-Chloro-5-fluorophenyl)-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of 6-(3-Chloro-5-Fluorophenyl)Picolinic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against comprehensive specifications, including identity confirmation, assay, and impurity profiling. A Certificate of Analysis (COA) documenting all test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider conditions under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.