Description

3-Chloro-4-Methylpicolinonitrile is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive nitrile and chloro substituents, which enable precise molecular construction in complex chemical pathways. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its picolinonitrile core structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Chloro-4-Methylpicolinonitrile
CAS No.	1261868-97-6
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	3-Chloro-4-methylpyridine-2-carbonitrile; 2-Cyano-3-chloro-4-methylpyridine; 4-Methyl-3-chloropicolinonitrile; 3-Chloro-4-methyl-2-pyridinecarbonitrile; 3-Chloro-4-methyl-2-cyanopyridine; 2-Pyridinecarbonitrile, 3-chloro-4-methyl-; Picolinonitrile, 3-chloro-4-methyl-
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-4-Methylpicolinonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the exacting standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.