Description

3-(2-(Trifluoromethyl)Phenyl)Pyridin-4-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique pyridine core substituted with a trifluoromethylphenyl group. This compound is valued for its role in modulating the biological activity and pharmacokinetic properties of target molecules, making it a critical building block in modern drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in areas requiring fluorine-containing scaffolds for enhanced metabolic stability and binding affinity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for potential oncology, CNS, and anti-inflammatory therapies.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Material Science: Serves as a functional monomer or ligand in the creation of specialty polymers, metal-organic frameworks (MOFs), or organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in the study of enzyme inhibition and protein-ligand interactions.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs focusing on structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-(2-(Trifluoromethyl)Phenyl)Pyridin-4-Amine
CAS No.	1261814-93-0
Molecular Formula	C12H9F3N2
Molecular Weight	238.21 g/mol
Synonyms	4-Amino-3-[2-(trifluoromethyl)phenyl]pyridine; 3-(2-(Trifluoromethyl)phenyl)-4-pyridinamine; 4-Pyridinamine, 3-[2-(trifluoromethyl)phenyl]-; 3-(α,α,α-Trifluoro-o-tolyl)-4-aminopyridine; 3-(2-Trifluoromethylphenyl)pyridin-4-ylamine; 3-(o-Trifluoromethylphenyl)-4-aminopyridine
EINECS	Contact for details

Quality Control

Our 3-(2-(Trifluoromethyl)Phenyl)Pyridin-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.