Description

5-Chloro-2,4-Difluorobenzoyl Chloride is a high-purity, multi-functional aromatic acid chloride intermediate essential for advanced organic synthesis. Its value lies in its dual reactive sites, enabling precise molecular construction for creating complex, high-performance compounds. This product is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty materials industries for synthesizing active ingredients and functional monomers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the chloro-difluoro substitution pattern enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated monomers and cross-linkers used in electronic display technologies and organic light-emitting diodes.
• Polymer Chemistry: Acts as a monomer or chain modifier in the synthesis of high-performance polymers, including polyamides and polyesters, for engineering plastics.
• Dyestuff & Pigment Manufacturing: Intermediate for producing specialized, light-fast azo dyes and complex organic pigments.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for creating biaryl structures in fine chemical synthesis.

Basic Information

Product Name	5-Chloro-2,4-Difluorobenzoyl Chloride
CAS No.	1261734-09-1
Molecular Formula	C7H2Cl2F2O
Molecular Weight	210.99 g/mol
Synonyms	2,4-Difluoro-5-chlorobenzoyl chloride; 5-Chloro-2,4-difluorobenzoic acid chloride; Benzoyl chloride, 5-chloro-2,4-difluoro-; 1261734-09-1; 5-Chloro-2,4-difluorobenzoic acid chloride; 2,4-Difluoro-5-chlorobenzoic acid chloride
EINECS	Contact for details

Quality Control

Our 5-Chloro-2,4-Difluorobenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; keep the container tightly sealed and handle under dry conditions or inert atmosphere to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.