Description

5-Hydroxy-2-Methylbenzoyl Chloride is a versatile and reactive organic intermediate, specifically an acyl chloride derivative of a substituted salicylic acid. Its primary value lies in its role as a key building block for synthesizing more complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), advanced agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, pain, and metabolic disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Dye and Pigment Manufacturing: Serves as a key intermediate for creating specialized azo dyes and high-performance pigments.
• Polymer Chemistry: Employed in the synthesis of monomers and polymers with specific functional properties, such as liquid crystal polymers.
• Organic Synthesis & Research: A valuable reagent for introducing the 5-hydroxy-2-methylbenzoyl moiety into target molecules in academic and industrial R&D labs.
• Fine Chemical Production: Used in the manufacture of complex fragrance ingredients, UV absorbers, and other specialty chemicals.

Basic Information

Item	Details
Product Name	5-Hydroxy-2-Methylbenzoyl Chloride
CAS No.	1261681-41-7
Molecular Formula	C9H7ClO2
Molecular Weight	182.60 g/mol
Synonyms	2-Methyl-5-hydroxybenzoyl chloride; 5-Hydroxy-o-toluoyl chloride; 2-Methyl-5-hydroxybenzoic acid chloride; 5-Hydroxy-2-methylbenzoic acid chloride; 2-Methyl-5-hydroxybenzoylchloride; 5-Hydroxy-2-methyl-benzoylchloride; (5-Hydroxy-2-methylphenyl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-2-Methylbenzoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.