Description

3-Bromopyrazin-2-Ol is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionality, serving as a key precursor for constructing complex molecular architectures in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists working in medicinal chemistry, where it is used to introduce the pyrazine pharmacophore and enable further functionalization. Its specific reactivity makes it a valuable intermediate for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the pyrazine core's bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional dyes due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences industry.
• Academic Research: Used in universities and research institutes for methodological studies in heterocyclic and cross-coupling chemistry.

Basic Information

Product Name	3-Bromopyrazin-2-Ol
CAS No.	1261634-06-3
Molecular Formula	C4H3BrN2O
Molecular Weight	174.98 g/mol
Synonyms	2-Hydroxy-3-bromopyrazine; 3-Bromo-2-pyrazinol; 3-Bromo-2(1H)-pyrazinone; 3-Bromopyrazin-2(1H)-one; 3-Bromo-1H-pyrazin-2-one; 2-Bromopyrazin-3-ol; 3-Bromo-2-hydroxypyrazine
EINECS	Contact for details

Quality Control

Our 3-Bromopyrazin-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment. We can support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.