Description

(8As)-Octahydro-8A-Methyl-Pyrrolo[1,2-A]Pyrazine is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrrolopyrazine bicyclic structure. This compound matters as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of novel therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers focused on drug discovery and process development for central nervous system (CNS) and other specialty medications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules, particularly in medicinal chemistry research.
• Drug Discovery & Development: Serves as a versatile scaffold for constructing novel chemical entities (NCEs) targeting specific biological pathways.
• Process Chemistry: Used in route scouting and optimization for the scalable production of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Pre-clinical Candidate Synthesis: Employed in the preparation of compounds for pharmacological screening and toxicology studies.

Basic Information

Product Name	(8As)-Octahydro-8A-Methyl-Pyrrolo[1,2-A]Pyrazine
CAS No.	1261569-85-0
Molecular Formula	C8H16N2
Molecular Weight	140.23 g/mol
Synonyms	8a-Methyloctahydropyrrolo[1,2-a]pyrazine; (8aS)-8a-Methylhexahydro-1H-pyrrolo[1,2-a]pyrazine; (8aS)-8a-Methyloctahydropyrrolo[1,2-a]pyrazine; Pyrrolo[1,2-a]pyrazine, octahydro-8a-methyl-, (8aS)-; (8aS)-8a-Methyl-1,2,3,5,6,7,8,8a-octahydropyrrolo[1,2-a]pyrazine; Chiral Pyrrolopyrazine Derivative; Bicyclic Tertiary Amine Intermediate
EINECS	Contact for details

Quality Control

Our (8As)-Octahydro-8A-Methyl-Pyrrolo[1,2-A]Pyrazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical characterization, including chiral purity verification. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.