Description

3-Iodo-5-Methyl-1-(Phenylsulfonyl)-1H-Pyrrolo-[2,3-B]Pyridine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for constructing targeted molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly in oncology and CNS therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile functional groups.
• API Development: Serves as a building block in the process development and scale-up of complex target molecules for clinical trials.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.

Basic Information

Product Name	3-Iodo-5-Methyl-1-(Phenylsulfonyl)-1H-Pyrrolo-[2,3-B]Pyridine-2-Carboxylic Acid
CAS No.	1261365-69-8
Molecular Formula	C₁₇H₁₁IN₂O₄S
Molecular Weight	466.25 g/mol
Synonyms	1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 3-iodo-5-methyl-1-(phenylsulfonyl)-; 3-Iodo-5-methyl-1-tosyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 1-(Benzenesulfonyl)-3-iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 3-Iodo-5-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; CAS 1261365-69-8
EINECS	Contact for details

Quality Control

Our 3-Iodo-5-Methyl-1-(Phenylsulfonyl)-1H-Pyrrolo-[2,3-B]Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.