Description

5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine-4-Carbaldehyde is a high-value, multi-functional heterocyclic building block characterized by its unique pyrrolopyridine core and trifluoromethyl group. This compound matters for its critical role in modern medicinal chemistry and agrochemical research, where it serves as a versatile scaffold for constructing novel bioactive molecules. Pharmaceutical and agrochemical R&D teams need this advanced intermediate to develop new drug candidates and crop protection agents, leveraging its structural complexity to modulate properties like metabolic stability, lipophilicity, and target binding affinity.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of small molecule drug candidates targeting various therapeutic areas, including oncology and central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a starting material for creating specialized organic electronic materials or ligands for catalytic systems.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine-4-Carbaldehyde
CAS No.	1261365-68-7
Molecular Formula	C9H5F3N2O
Molecular Weight	214.15 g/mol
Synonyms	4-Pyridinecarboxaldehyde, 5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-; 1H-Pyrrolo[2,3-b]pyridine-4-carbaldehyde, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-4-carboxaldehyde; 5-Trifluoromethyl-1H-pyrrolo[2,3-b]pyridine-4-carbaldehyde; 1261365-68-7; 5-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-4-aldehyde
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridine-4-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, impurities, and full characterization data are provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.