Description

2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-7-ol is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its crucial role in the synthesis of complex molecules, particularly in medicinal chemistry where its fused dioxino-pyridine structure offers unique electronic and spatial properties. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Employed in the synthesis of more complex heterocyclic systems and functionalized molecules due to its reactive hydroxyl group and fused ring system.
• Agrochemical Research: Potential intermediate in the development of novel pesticides and herbicides, leveraging its unique bicyclic structure.
• Material Science Precursor: Investigated for the synthesis of specialized ligands, catalysts, or organic electronic materials.

Basic Information

Product Name	2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-7-ol
CAS No.	1261365-65-4
Molecular Formula	C9H9NO3
Molecular Weight	179.17 g/mol
Synonyms	7-Hydroxy-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine; [1,4]Dioxino[2,3-b]pyridin-7-ol, 2,3-dihydro-; 2,3-Dihydro-1,4-dioxino[2,3-b]pyridin-7-ol; 7-Hydroxydioxinopyridine; DHPO; Fused dioxinopyridine derivative
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-7-ol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive R&D and scale-up processes. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.