Description

2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine-7-carbonitrile is a high-value heterocyclic organic compound featuring a fused dioxino-pyridine core structure with a nitrile functional group. This molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Used in the research and synthesis of new-generation herbicides, fungicides, and insecticides.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Precursor: Acts as a building block for organic electronic materials and functional polymers.

Basic Information

Product Name	2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine-7-carbonitrile
CAS No.	1261365-28-9
Molecular Formula	C9H6N2O2
Molecular Weight	174.16 g/mol
Synonyms	7-Cyano-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine; [1,4]Dioxino[2,3-b]pyridine-7-carbonitrile, 2,3-dihydro-; 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine-7-carbonitrile; Dioxinopyridinecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine-7-carbonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.