Description

2-Amino-3-Chloropyridin-4-Ol is a high-purity, multi-functional pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique halogenated and amino-substituted structure makes it an indispensable intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a functional monomer or ligand precursor in the creation of specialized polymers, metal-organic frameworks (MOFs), and coordination complexes.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis for drug discovery.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized heterocyclic dyes and colorants for technical applications.

Basic Information

Product Name	2-Amino-3-Chloropyridin-4-Ol
CAS No.	1261269-43-5
Molecular Formula	C5H5ClN2O
Molecular Weight	144.56 g/mol
Synonyms	4-Hydroxy-3-chloro-2-aminopyridine; 3-Chloro-2-amino-4-pyridinol; 2-Amino-3-chloro-4-hydroxypyridine; 3-Chloro-2-aminopyridin-4-ol; 2-Amino-3-chloro-4-pyridol; 3-Chloro-4-hydroxy-2-aminopyridine; 4-Pyridinol, 2-amino-3-chloro-
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3-Chloropyridin-4-Ol is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure reliable purity and consistent batch-to-batch performance for your critical synthesis workflows. Certificates of Analysis (COA) detailing identity, purity (typically >97% by HPLC), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.