Description

[1-(3-Chloro-Benzyl)-Piperidin-3-Yl]-Methyl-Amine Hydrochloride is a high-purity, specialized organic intermediate with the CAS registry number 1261231-75-7. This compound is a critical building block in modern pharmaceutical research and development, valued for its piperidine-based structure which is a common pharmacophore. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active pharmaceutical ingredients (APIs) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, receptor modulators, and other therapeutic agents.
• Agrochemical Research: Used in the development of new crop protection agents and pesticides, leveraging its halogenated benzyl and amine functionalities.
• Chemical Biology & Proteomics: Serves as a versatile scaffold or linker for creating chemical probes, inhibitors, and tool compounds for biological target identification and validation.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the exploration of new synthetic pathways in organic chemistry.
• Custom Synthesis & Scale-Up: A starting material for custom synthesis projects, supporting process chemistry from milligram to kilogram scale for pre-clinical and clinical trial material production.

Basic Information

Product Name	[1-(3-Chloro-Benzyl)-Piperidin-3-Yl]-Methyl-Amine Hydrochloride
CAS No.	1261231-75-7
Molecular Formula	C14H22Cl2N2
Molecular Weight	289.25 g/mol
Synonyms	1-[(3-Chlorophenyl)methyl]-3-(methylamino)piperidine hydrochloride; 3-(Methylamino)-1-(3-chlorobenzyl)piperidine HCl; 1-(3-Chlorobenzyl)-3-(methylamino)piperidine hydrochloride; N-Methyl-1-(3-chlorobenzyl)piperidin-3-amine hydrochloride; 1-(3-Chloro-benzyl)-piperidin-3-yl-methyl-amine HCl; (1-(3-Chlorobenzyl)piperidin-3-yl)methanamine hydrochloride
EINECS	Contact for details

Quality Control

Our [1-(3-Chloro-Benzyl)-Piperidin-3-Yl]-Methyl-Amine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.