Description

4-[(6-Bromo-Pyridin-2-Yl)-Methyl-Amino]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex molecules, offering a versatile piperidine scaffold with a bromopyridine moiety for further functionalization. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a key starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Ligand Synthesis: The bromopyridine group allows for cross-coupling reactions, making it valuable for creating complex ligands in catalysis.
• Chemical Biology Probes: Utilized in the development of molecular probes for target identification and validation in biological systems.
• Agrochemical Research: Potential application as an intermediate in the development of novel crop protection agents.

Basic Information

Product Name	4-[(6-Bromo-Pyridin-2-Yl)-Methyl-Amino]-Piperidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1261231-17-7
Molecular Formula	C17H26BrN3O2
Molecular Weight	384.31 g/mol
Synonyms	tert-Butyl 4-[(6-bromopyridin-2-yl)(methyl)amino]piperidine-1-carboxylate; 1-Boc-4-[(6-bromo-2-pyridyl)-N-methyl-amino]piperidine; 4-[(6-Bromo-2-pyridinyl)(methyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-[(6-bromopyridin-2-yl)(methyl)amino]piperidine; N-(6-Bromo-2-pyridyl)-N-methyl-4-piperidinamine 1-Boc derivative; 4-[(6-Bromo-pyridin-2-yl)-methyl-amino]-piperidine-1-carboxylic acid tert-butyl ester; BOC-4-[(6-Bromo-2-pyridyl)-N-methyl-amino]piperidine
EINECS	Contact for details

Quality Control

Our 4-[(6-Bromo-Pyridin-2-Yl)-Methyl-Amino]-Piperidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development from research to commercial scale with quality standards suitable for cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.