Description

tert-Butyl 4-(3-Bromo-2-Cyanophenyl)-Piperazine-1-Carboxylate is a high-value, multi-functional piperazine derivative and a crucial synthetic intermediate in advanced organic chemistry. Its core value lies in providing a protected piperazine scaffold with orthogonal reactive sites, enabling precise and modular construction of complex molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring complex heterocyclic structures.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for creating molecular probes, enzyme inhibitors, and tool compounds for biological target validation.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & R&D Laboratories: Used in methodological research and the discovery of new synthetic routes involving piperazine chemistry.

Basic Information

Product Name	tert-Butyl 4-(3-Bromo-2-Cyanophenyl)-Piperazine-1-Carboxylate
CAS No.	1260898-57-4
Molecular Formula	C16H20BrN3O2
Molecular Weight	366.26 g/mol
Synonyms	1-Boc-4-(3-bromo-2-cyanophenyl)piperazine; tert-Butyl 4-(3-bromo-2-cyanophenyl)piperazine-1-carboxylate; 3-Bromo-2-(4-(tert-butoxycarbonyl)piperazin-1-yl)benzonitrile; 1-(tert-Butoxycarbonyl)-4-(3-bromo-2-cyanophenyl)piperazine; BOC-3-Bromo-2-cyanophenylpiperazine; 1260898-57-4; 4-(3-Bromo-2-cyanophenyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl 4-(3-Bromo-2-Cyanophenyl)-Piperazine-1-Carboxylate undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality management system is designed to meet the stringent requirements of research and development as well as pre-clinical scale-up. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by NMR and IR), and impurity profile is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.