Description

4-Aminopiperidin-2-One Hydrochloride is a high-purity pharmaceutical intermediate and versatile organic building block. Its value lies in its functionalized piperidinone core, which is a privileged scaffold in medicinal chemistry for constructing bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on synthesizing novel drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in the discovery and optimization of new drug candidates, leveraging its amine and amide functionalities for structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides and herbicides, where the piperidinone structure can impart specific biological activity.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tool compounds for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) producing specialized fine chemicals.

Basic Information

Product Name	4-Aminopiperidin-2-One Hydrochloride
CAS No.	1260883-24-6
Molecular Formula	C5H11N2O·HCl
Molecular Weight	150.62 g/mol (Free base: 114.16)
Synonyms	4-Amino-2-piperidinone hydrochloride; 4-Amino-2-piperidone hydrochloride; 2-Piperidinone, 4-amino-, hydrochloride; 4-Aminopiperidin-2-one HCl; 4-Amino-delta2-piperidinone hydrochloride; 4-Amino-2-oxopiperidine hydrochloride; 4-Aminopiperidinone hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Aminopiperidin-2-One Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We adhere to current Good Manufacturing Practices (cGMP) where applicable. Comprehensive analytical testing is performed, and a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.