Description

tert-Butyl 7-Oxo-Hexahydro-1H-Pyrido[1,2-A]Pyrazine-2(6H)-Carboxylate CAS NO 1260863-04-4 is a high-purity, advanced pharmaceutical intermediate characterized by its bicyclic piperazine-pyridine core structure. This compound is of significant value in modern organic synthesis, serving as a critical building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process chemistry.

Application

• Key Intermediate in API Synthesis: Serves as a crucial precursor in the multi-step synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Pharmaceutical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of new chemical entities (NCEs).
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable, cost-effective manufacturing routes for candidate drugs.
• Building Block for Heterocyclic Chemistry: Its fused ring system makes it a valuable scaffold for constructing more complex polycyclic compounds with potential biological activity.
• Contract Manufacturing (CMO/CDMO): Supplied to contract development and manufacturing organizations for the production of clinical trial materials and commercial APIs.

Basic Information

Product Name	tert-Butyl 7-Oxo-Hexahydro-1H-Pyrido[1,2-A]Pyrazine-2(6H)-Carboxylate
CAS No.	1260863-04-4
Molecular Formula	C14H22N2O3
Molecular Weight	266.34 g/mol
Synonyms	tert-Butyl 7-oxohexahydro-1H-pyrido[1,2-a]pyrazine-2(6H)-carboxylate; 2-Boc-7-oxo-hexahydro-1H-pyrido[1,2-a]pyrazine; 1,2,3,6,7,8-Hexahydro-2-[(1,1-dimethylethoxy)carbonyl]pyrido[1,2-a]pyrazin-7-one; 7-Oxo-hexahydro-1H-pyrido[1,2-a]pyrazine-2-carboxylic acid tert-butyl ester; Boc-7-oxo-hexahydro-1H-pyrido[1,2-a]pyrazine; 1260863-04-4; tert-Butyl 7-oxo-1,2,3,6,7,8-hexahydropyrido[1,2-a]pyrazine-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 7-Oxo-Hexahydro-1H-Pyrido[1,2-A]Pyrazine-2(6H)-Carboxylate adheres to stringent quality management systems, ensuring batch-to-batch consistency and high purity suitable for pharmaceutical R&D. All materials are characterized and released against comprehensive specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5% Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.