Description

(6-(Piperidin-4-Yl)Pyridin-2-Yl)Methanol Dihydrochloride is a high-purity organic salt building block of significant interest in advanced pharmaceutical research and development. This compound matters as a critical intermediate for synthesizing novel small molecule therapeutics, particularly those targeting central nervous system and oncological pathways. It is primarily needed by medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries for drug discovery and API synthesis programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and receptor modulator research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for developing new therapeutic agents.
• Chemical Biology: Serves as a probe or precursor for bioactive molecules in target identification and validation studies.
• Process Chemistry: Employed in the scale-up and route development for Active Pharmaceutical Ingredient (API) manufacturing.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized compounds for client projects.
• Library Synthesis: Used to generate focused chemical libraries for high-throughput screening in drug discovery campaigns.

Basic Information

Product Name	(6-(Piperidin-4-Yl)Pyridin-2-Yl)Methanol Dihydrochloride
CAS No.	1260856-19-6
Molecular Formula	C11H16N2O · 2HCl
Molecular Weight	265.18 g/mol (Free base: 192.26 g/mol)
Synonyms	2-(Hydroxymethyl)-6-(4-piperidinyl)pyridine dihydrochloride; (6-(4-Piperidinyl)-2-pyridinyl)methanol dihydrochloride; 6-(Piperidin-4-yl)pyridine-2-methanol dihydrochloride; 2-Pyridinemethanol, 6-(4-piperidinyl)-, dihydrochloride; 6-(4-Piperidyl)pyridin-2-ylmethanol dihydrochloride; (6-(1-Piperidinyl)pyridin-2-yl)methanol dihydrochloride (isomer); UNII-Contact for details
EINECS	Contact for details

Quality Control

Our (6-(Piperidin-4-Yl)Pyridin-2-Yl)Methanol Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure compliance with research-grade and custom synthesis specifications. Certificates of Analysis (COA) with complete analytical data are provided to guarantee traceability, consistency, and reliability for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.