Description

1-(5-Fluoropyridin-2-Yl)Cyclopropanamine is a high-value fluorinated pyridine derivative featuring a cyclopropanamine moiety, serving as a critical building block in modern synthetic chemistry. Its unique structure makes it an essential intermediate for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand & Catalyst Development: Used in organometallic chemistry to create novel ligands for catalytic processes.
• Material Science Research: Precursor for synthesizing functionalized polymers and advanced organic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological pathways and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	1-(5-Fluoropyridin-2-Yl)Cyclopropanamine
CAS No.	1260830-75-8
Molecular Formula	C8H9FN2
Molecular Weight	152.17 g/mol
Synonyms	1-(5-Fluoropyridin-2-yl)cyclopropanamine; 2-(1-Aminocyclopropyl)-5-fluoropyridine; 5-Fluoro-2-(1-aminocyclopropyl)pyridine; 1-(5-Fluoro-2-pyridinyl)cyclopropanamine; Cyclopropanamine, 1-(5-fluoropyridin-2-yl)-; 1260830-75-8; 5-Fluoro-2-cyclopropylaminopyridine (related structure).
EINECS	Contact for details

Quality Control

Our 1-(5-Fluoropyridin-2-Yl)Cyclopropanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.