Description

2-(Azetidin-3-Yl)-6-Fluoropyridine Dihydrochloride is a high-purity, heterocyclic organic compound featuring a fused azetidine and fluoropyridine structure. This compound serves as a critical pharmaceutical intermediate and building block in modern medicinal chemistry, enabling the synthesis of novel active ingredients. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of targeted protein degraders.
• Covalent Inhibitor Synthesis: The azetidine moiety can be utilized to create irreversible enzyme inhibitors for therapeutic applications.
• Chemical Biology Probes: Employed in the synthesis of tool compounds for investigating biological pathways and target validation.
• Agrochemical Research: Acts as an intermediate in the development of new crop protection agents and pesticides.
• Academic Research: Used in universities and institutes for methodological studies in heterocyclic and fluorine chemistry.

Basic Information

Product Name	2-(Azetidin-3-Yl)-6-Fluoropyridine Dihydrochloride
CAS No.	1260828-79-2
Molecular Formula	C8H10Cl2FN3
Molecular Weight	238.09 g/mol
Synonyms	6-Fluoro-2-(3-azetidinyl)pyridine dihydrochloride; 2-(Azetidin-3-yl)-6-fluoropyridine hydrochloride (1:2); 3-(6-Fluoropyridin-2-yl)azetidine dihydrochloride; 6-Fluoro-2-(azetidin-3-yl)pyridine dihydrochloride; Azetidine, 3-(6-fluoro-2-pyridinyl)-, hydrochloride (1:2); 2-(3-Azetidinyl)-6-fluoropyridine dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-(Azetidin-3-Yl)-6-Fluoropyridine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.