Description

3-Methyl-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine hydrochloride is a high-purity, heterocyclic organic compound that serves as a critical building block in modern pharmaceutical research and development. This compound matters because it provides a versatile and structurally defined scaffold for medicinal chemists to create novel drug candidates targeting a range of central nervous system and other therapeutic areas. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to accelerate their synthesis programs and ensure the integrity of their final active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• API Synthesis: Employed in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) that incorporate the triazolopyrazine moiety.
• Biochemical Tool Compound: Serves as a research chemical for probing biological pathways and validating new therapeutic targets in preclinical studies.
• Fine Chemical Production: Supplied to custom synthesis and contract manufacturing organizations (CMOs) for the production of specialized, high-value compounds.

Basic Information

Product Name	3-Methyl-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
CAS No.	1260826-85-4
Molecular Formula	C7H13ClN4
Molecular Weight	188.66 g/mol
Synonyms	3-Methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine HCl; 3-Methyl-4,5,6,7-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine hydrochloride; 1-Methyl-4,5,6,7-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine hydrochloride; Triazolopyrazine hydrochloride derivative; CAS 1260826-85-4
EINECS	Contact for details

Quality Control

Our 3-Methyl-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.