Description

(5-Fluoro-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester is a high-value fluorinated pyridine derivative and a key protected intermediate in advanced organic synthesis. Its primary commercial value lies in its role as a versatile building block for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research and development chemists and process scale-up teams working on active pharmaceutical ingredients (APIs), crop protection agents, and novel materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used to construct fluorinated pyridine cores found in modern herbicides, fungicides, and insecticides, enhancing their biological activity and environmental stability.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and the exploration of new chemical entities.
• Process Chemistry & Scale-Up: Employed in the development and optimization of robust, cost-effective manufacturing routes for commercial-scale production of target molecules.
• Ligand & Catalyst Development: The fluoropyridine moiety can be utilized to create specialized ligands for catalysis or as a component in functional materials.

Basic Information

Product Name	(5-Fluoro-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	1260794-50-0
Molecular Formula	C10H13FN2O2
Molecular Weight	212.22 g/mol
Synonyms	tert-Butyl (5-fluoropyridin-2-yl)carbamate; N-Boc-5-fluoro-2-aminopyridine; 2-((tert-Butoxycarbonyl)amino)-5-fluoropyridine; 5-Fluoro-2-pyridinylcarbamic Acid 1,1-Dimethylethyl Ester; Boc-5-Fluoro-2-aminopyridine; N-Boc-2-Amino-5-fluoropyridine; 5-Fluoro-2-aminopyridine N-Boc protected; 2-Amino-5-fluoropyridine N-Boc derivative
EINECS	Contact for details

Quality Control

Our production of (5-Fluoro-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.