Description

Methyl 5-(Aminomethyl)Nicotinate Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant commercial interest. Its molecular structure, featuring both an ester and a primary amine hydrochloride salt, makes it a versatile precursor for synthesizing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors. Its reliable quality and consistent supply are critical for downstream process development and scale-up.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the nicotinate scaffold.
• Chemical Biology Research: Serves as a versatile scaffold or linker for creating probes and tool compounds in medicinal chemistry programs.
• Peptide Mimetic Development: The aminomethyl group facilitates its incorporation into peptide-like structures to modulate biological activity.
• Ligand and Catalyst Preparation: Utilized in the preparation of specialized ligands for metal catalysis or as a precursor for functionalized materials.

Basic Information

Product Name	Methyl 5-(Aminomethyl)Nicotinate Hydrochloride
CAS No.	1260791-59-0
Molecular Formula	C8H11N2O2•HCl
Molecular Weight	202.64 g/mol
Synonyms	5-(Aminomethyl)nicotinic acid methyl ester hydrochloride; Methyl 5-(aminomethyl)pyridine-3-carboxylate hydrochloride; 3-Pyridinecarboxylic acid, 5-(aminomethyl)-, methyl ester, hydrochloride; Nicotinic acid, 5-(aminomethyl)-, methyl ester, hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 5-(Aminomethyl)Nicotinate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.