Description

2-Chloro-5-(Trifluoromethyl)Pyridine-4-Carbonitrile is a high-value, multi-functional pyridine derivative and a key synthetic building block in advanced organic chemistry. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

This versatile intermediate serves as a critical precursor in several high-tech applications:

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	2-Chloro-5-(Trifluoromethyl)Pyridine-4-Carbonitrile
CAS No.	1260782-19-1
Molecular Formula	C7H2ClF3N2
Molecular Weight	206.55 g/mol
Synonyms	4-Cyano-2-chloro-5-(trifluoromethyl)pyridine; 2-Chloro-5-trifluoromethyl-4-cyanopyridine; 2-Chloro-4-cyano-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-chloropyridine-4-carbonitrile; 2-Chloro-α,α,α-trifluoro-4-pyridineacetonitrile; Pyridine, 2-chloro-5-(trifluoromethyl)-4-cyano-; 1260782-19-1
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-5-(Trifluoromethyl)Pyridine-4-Carbonitrile adheres to stringent quality management protocols. Every batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all critical specifications. We operate under a quality system designed to meet the rigorous standards required for pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or amber glass until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.