Description

2-(Azetidin-3-Yl)-5-(Trifluoromethyl)Pyridine is a high-value, heterocyclic organic compound featuring a fused azetidine and pyridine ring system with a trifluoromethyl substituent. This unique structure makes it a critical pharmaceutical intermediate and building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its unique azetidine-pyridine scaffold.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced crop protection agents and herbicides.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex heterocyclic architectures.

Basic Information

Product Name	2-(Azetidin-3-Yl)-5-(Trifluoromethyl)Pyridine
CAS No.	1260779-70-1
Molecular Formula	C9H9F3N2
Molecular Weight	202.18 g/mol
Synonyms	3-(5-(Trifluoromethyl)pyridin-2-yl)azetidine; 2-(Azetidin-3-yl)-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2-(3-azetidinyl)pyridine; Azetidine, 3-[5-(trifluoromethyl)-2-pyridinyl]-; 3-(5-Trifluoromethylpyridin-2-yl)azetidine
EINECS	Contact for details

Quality Control

Our 2-(Azetidin-3-Yl)-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency essential for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.