Description

2-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-7-Carboxylic Acid is a high-value, multifunctional heterocyclic building block characterized by its imidazopyridine core and trifluoromethyl substituent. This compound is essential for medicinal chemistry research and development, offering significant potential for modulating the pharmacokinetic and physicochemical properties of novel drug candidates. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of advanced intermediates for active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology, CNS disorders, and anti-infective therapies.
• Medicinal Chemistry Building Block: Used to introduce the imidazopyridine scaffold and trifluoromethyl group, which can enhance metabolic stability, lipophilicity, and binding affinity in lead optimization.
• Agrochemical Research: Serves as a precursor in the development of novel pesticides and herbicides, leveraging its unique heterocyclic structure.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials, ligands for catalysis, or advanced polymers.
• Biochemical Tool Compound: Used in life science research as a probe or inhibitor to study specific biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	2-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-7-Carboxylic Acid
CAS No.	1260777-52-3
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.15 g/mol
Synonyms	2-(Trifluoromethyl)-7-imidazo[1,2-a]pyridinecarboxylic acid; Imidazo[1,2-a]pyridine-7-carboxylic acid, 2-(trifluoromethyl)-; 2-Trifluoromethylimidazo[1,2-a]pyridine-7-carboxylic acid; 7-Carboxy-2-trifluoromethylimidazo[1,2-a]pyridine; 1260777-52-3; 2-CF3-Imidazo[1,2-a]pyridine-7-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Imidazo[1,2-A]Pyridine-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and regulatory compliance (including REACH) ensures a reliable supply for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.