Description

3-Chloro-1H-Pyrazolo[3,4-B]Pyrazine is a high-purity heterocyclic organic compound, identified by CAS NO 1260773-79-2, that serves as a critical building block in advanced chemical synthesis. Its unique fused pyrazolo-pyrazine core with a reactive chloro substituent makes it an invaluable intermediate for pharmaceutical research and development. This compound is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a starting material for creating specialized heterocyclic ligands and organic electronic materials.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects and library production.

Basic Information

Product Name	3-Chloro-1H-Pyrazolo[3,4-B]Pyrazine
CAS No.	1260773-79-2
Molecular Formula	C5H3ClN4
Molecular Weight	154.56 g/mol
Synonyms	3-Chloro-1H-pyrazolo[3,4-b]pyrazine; 3-Chloro-1H-pyrazolo[3,4-b]pyrazine; 1H-Pyrazolo[3,4-b]pyrazine, 3-chloro-; 3-Chloro-1H-pyrazolo[3,4-b]pyrazine (CAS 1260773-79-2); 3-Chloro-1H-pyrazolo[3,4-b]pyrazine; 3-Chloro-1H-pyrazolo[3,4-b]pyrazine
EINECS	Contact for details

Quality Control

Our 3-Chloro-1H-Pyrazolo[3,4-B]Pyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.