Description

Methyl 4-Chloro-3-Methylpicolinate CAS NO 1260764-76-8 is a high-purity, versatile picolinate ester derivative, serving as a critical synthetic intermediate in advanced organic synthesis. Its value lies in providing a functionalized pyridine core that enables the construction of complex molecules with precision. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other heterocyclic drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, coordination polymers, and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	Methyl 4-Chloro-3-Methylpicolinate
CAS No.	1260764-76-8
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	Methyl 4-chloro-3-methylpyridine-2-carboxylate; 4-Chloro-3-methylpicolinic acid methyl ester; 2-Pyridinecarboxylic acid, 4-chloro-3-methyl-, methyl ester; 3-Methyl-4-chloropicolinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-Chloro-3-Methylpicolinate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.