Description

2-Chloro-5,6,7,8-Tetrahydro-Pyrido[3,4-B]Pyrazine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Employed in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Library Synthesis for High-Throughput Screening: A valuable reactant for generating diverse compound libraries to identify new bioactive molecules.
• Fine Chemical Production: Acts as a precursor in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-Chloro-5,6,7,8-Tetrahydro-Pyrido[3,4-B]Pyrazine
CAS No.	1260670-14-1
Molecular Formula	C7H8ClN3
Molecular Weight	169.61 g/mol
Synonyms	2-Chloro-5,6,7,8-tetrahydropyrido[3,4-b]pyrazine; 5,6,7,8-Tetrahydro-2-chloropyrido[3,4-b]pyrazine; Pyrido[3,4-b]pyrazine, 2-chloro-5,6,7,8-tetrahydro-; 2-Chloro-5,6,7,8-tetrahydro-pyrido[3,4-b]pyrazine; 1260670-14-1; AKOS006361889; ZINC000644019789
EINECS	Contact for details

Quality Control

Our 2-Chloro-5,6,7,8-Tetrahydro-Pyrido[3,4-B]Pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.