Description

1,7-Naphthyridine, 4-Bromo-5,6,7,8-Tetrahydro- is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated, saturated heterocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the construction of complex molecular libraries for high-throughput screening.
• Organic Synthesis Building Block: The bromine atom provides a versatile handle for further functionalization via cross-coupling reactions (e.g., Suzuki, Negishi).
• Ligand and Catalyst Development: Potential use in the synthesis of novel chelating ligands or organocatalysts due to the nitrogen-rich naphthyridine core.
• Agrochemical Research: Employed in the research and development of new crop protection agents and pesticides.
• Material Science Precursor: Can be utilized in the synthesis of organic electronic materials or metal-organic frameworks (MOFs).

Basic Information

Product Name	1,7-Naphthyridine, 4-Bromo-5,6,7,8-Tetrahydro-
CAS No.	1260670-11-8
Molecular Formula	C11H11BrN2
Molecular Weight	251.12 g/mol
Synonyms	4-Bromo-5,6,7,8-tetrahydro-1,7-naphthyridine; 4-Bromo-5,6,7,8-tetrahydro-1,7-naphthyridine; 5,6,7,8-Tetrahydro-4-bromo-1,7-naphthyridine; 4-Bromotetrahydro-1,7-naphthyridine; Bromotetrahydro-naphthyridine; 1,7-Naphthyridine, 4-bromo-5,6,7,8-tetrahydro-; Tetrahydro-4-bromo-1,7-naphthyridine
EINECS	Contact for details

Quality Control

Our 1,7-Naphthyridine, 4-Bromo-5,6,7,8-Tetrahydro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.