Description

3-Bromo-8-Chloro-[1,7]Naphthyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique halogenated naphthyridine scaffold, which provides versatile reactivity for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other biologically active molecules targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology: Employed as a molecular probe or a tag in the study of biological processes and protein interactions.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination, enabling rapid diversification of the naphthyridine core.
• Library Synthesis: A valuable scaffold for generating diverse compound libraries in high-throughput screening for drug discovery.

Basic Information

Product Name	3-Bromo-8-Chloro-[1,7]Naphthyridine
CAS No.	1260670-05-0
Molecular Formula	C8H4BrClN2
Molecular Weight	243.49 g/mol
Synonyms	3-Bromo-8-chloro-1,7-naphthyridine; 8-Chloro-3-bromo[1,7]naphthyridine; 1,7-Naphthyridine, 3-bromo-8-chloro-; 1260670-05-0; 3-Br-8-Cl-[1,7]Naphthyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-8-Chloro-[1,7]Naphthyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment is to supply material that meets the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.