Description

5-Chloro-4-Iodopyridin-2-Amine is a halogenated pyridine derivative serving as a versatile and critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional agrochemicals, where its unique substitution pattern enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Functional Material Research: Acts as a building block for organic electronic materials and advanced polymers.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	5-Chloro-4-Iodopyridin-2-Amine
CAS No.	1260667-65-9
Molecular Formula	C5H4ClIN2
Molecular Weight	254.46 g/mol
Synonyms	2-Amino-5-chloro-4-iodopyridine; 4-Iodo-5-chloropyridin-2-amine; 5-Chloro-4-iodo-2-pyridinamine; 5-Chloro-4-iodo-2-aminopyridine; 2-Pyridinamine, 5-chloro-4-iodo-; 4-Iodo-5-chloro-2-aminopyridine; 5-Chloro-4-iodopyridin-2-ylamine
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-Iodopyridin-2-Amine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The product is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.