Description

2-Pyrazinamine, 3-Chloro-5-(Trifluoromethyl)- is a high-value, multi-functional heterocyclic building block characterized by its pyrazine core substituted with chloro and trifluoromethyl groups. This compound is essential for advanced organic synthesis, offering a versatile scaffold for constructing complex molecules with tailored properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective therapeutics.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazine scaffold.
• Material Science: Serves as a building block for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Acts as a versatile reagent for introducing the 3-chloro-5-(trifluoromethyl)pyrazin-2-amine moiety into more complex molecular architectures.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and discovery chemistry projects.

Basic Information

Product Name	2-Pyrazinamine, 3-Chloro-5-(Trifluoromethyl)-
CAS No.	1260667-12-6
Molecular Formula	C5H3ClF3N3
Molecular Weight	197.55 g/mol
Synonyms	3-Chloro-5-(trifluoromethyl)pyrazin-2-amine; 3-Chloro-5-(trifluoromethyl)-2-pyrazinamine; 2-Amino-3-chloro-5-(trifluoromethyl)pyrazine; 3-Chloro-5-trifluoromethylpyrazin-2-ylamine; 1260667-12-6; 3-Chloro-5-(trifluoromethyl)pyrazine-2-amine
EINECS	Contact for details

Quality Control

Our 2-Pyrazinamine, 3-Chloro-5-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is sensitive to fluoride/strong alkali conditions; ensure appropriate segregation in storage. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.